Can we detect life in unexpected radical forms or only life as we know it? How do we look for interstellar communications (radio/laser), biosignatures (atmospheric signs of life on exoplanets) and technosignatures (e.g. megastructures like Dyson Spheres)? What do exoplanet discoveries and new Webb Space Telescope results tell us? Can an interstellar object transiting our solar system, the asteroid Oumuamua, be an alien probe as suggested by a Harvard astronomer? Could fluctuations in Tabby’s star indicate an alien megastructure? Is silicon life possible (Star Trek Horta)? Could life take the form of city-sized atmospheric jellyfish, clouds of ionized gas, or be powered by nuclear reactions? Explore these topics in a fascinating introduction to what we know, suspect and speculate about life in the universe.